Orientals and cubes, inductively

We provide direct inductive constructions of the orientals and the cubes, exhibiting them as the iterated cones, respectively, the iterated cylinders, of the terminal strict globular omega-category.Comment: 19 page

The Catalan simplicial set

The Catalan numbers are well-known to be the answer to many different counting problems, and so there are many different families of sets whose cardinalities are the Catalan numbers. We show how such a family can be given the structure of a simplicial set. We show how the low-dimensional parts of this simplicial set classify, in a precise sense, the structures of monoid and of monoidal category. This involves aspects of combinatorics, algebraic topology, quantum groups, logic, and category theory.Comment: 15 pages. Replaces and expands upon parts of arXiv:1307.0265; remaining parts of arXiv:1307.0265 will be incorporated into a sequel. Version 2: minor revision; to appear in Math. Proc. Camb. Phil. So

Analyzing the Resettlement of Puerto Ricans Post-Hurricane Maria in Worcester

On September 20, 2017, Hurricane Maria made landfall on Puerto Rico, devastating the island and prompting an exodus of Puerto Ricans to the U.S. mainland. Projections of these migration numbers range widely. For our project, we made informed predictions of how many Puerto Ricans may arrive in the City of Worcester, Massachusetts and investigated what resources are critical for their resettlement

A Putative Multiple-Demand System in the Macaque Brain.

UNLABELLED: In humans, cognitively demanding tasks of many types recruit common frontoparietal brain areas. Pervasive activation of this "multiple-demand" (MD) network suggests a core function in supporting goal-oriented behavior. A similar network might therefore be predicted in nonhuman primates that readily perform similar tasks after training. However, an MD network in nonhuman primates has not been described. Single-cell recordings from macaque frontal and parietal cortex show some similar properties to human MD fMRI responses (e.g., adaptive coding of task-relevant information). Invasive recordings, however, come from limited prespecified locations, so they do not delineate a macaque homolog of the MD system and their positioning could benefit from knowledge of where MD foci lie. Challenges of scanning behaving animals mean that few macaque fMRI studies specifically contrast levels of cognitive demand, so we sought to identify a macaque counterpart to the human MD system using fMRI connectivity in 35 rhesus macaques. Putative macaque MD regions, mapped from frontoparietal MD regions defined in humans, were found to be functionally connected under anesthesia. To further refine these regions, an iterative process was used to maximize their connectivity cross-validated across animals. Finally, whole-brain connectivity analyses identified voxels that were robustly connected to MD regions, revealing seven clusters across frontoparietal and insular cortex comparable to human MD regions and one unexpected cluster in the lateral fissure. The proposed macaque MD regions can be used to guide future electrophysiological investigation of MD neural coding and in task-based fMRI to test predictions of similar functional properties to human MD cortex. SIGNIFICANCE STATEMENT: In humans, a frontoparietal "multiple-demand" (MD) brain network is recruited during a wide range of cognitively demanding tasks. Because this suggests a fundamental function, one might expect a similar network to exist in nonhuman primates, but this remains controversial. Here, we sought to identify a macaque counterpart to the human MD system using fMRI connectivity. Putative macaque MD regions were functionally connected under anesthesia and were further refined by iterative optimization. The result is a network including lateral frontal, dorsomedial frontal, and insular and inferior parietal regions closely similar to the human counterpart. The proposed macaque MD regions can be useful in guiding electrophysiological recordings or in task-based fMRI to test predictions of similar functional properties to human MD cortex

Clean Paraguay: Reducing Litter through Education and Participation

https://digitalcommons.wpi.edu/gps-posters/1653/thumbnail.jp

Phosphodiesterase-5 inhibitors in management of pulmonary hypertension: safety, tolerability, and efficacy

Pulmonary arterial hypertension (PAH) is a progressive disease that causes severe disability and has no cure. Over the past 20 years, a variety of treatment options have evolved for the management of PAH. With an expanded therapeutic armamentarium come more complex decisions regarding treatment options. Agent selection depends upon several factors including efficacy, side effect profile, and cost, as well as convenience of administration. We have undertaken a review of phosphodiesterase-5 (PDE-5) inhibitors in PAH with a focus on efficacy and safety. A literature search was conducted using the Medline and Cochrane Central Register of Controlled Trials databases (1966–February 2010) for relevant randomized clinical studies. Overall, 10 studies met our inclusion criteria. Sildenafil was the most commonly studied agent, followed by tadalafil and vardenafil. Most trials found that the PDE-5 inhibitors significantly improved exercise capacity and lowered pulmonary pressures. However, there were conflicting results regarding these agents’ impact on improving cardiac function and functional class. Overall, these medications were effective and well tolerated with a relatively benign side effect profile. The PDE-5 inhibitors are an important option in treating PAH. While most of the published clinical data involved sildenafil, the other PDE-5 inhibitors show promise as well. Further studies are needed to determine the optimal doses of this therapeutic drug class, as well as its effects as adjunctive therapy with other agents in PAH

Internet Safety: Positioning VCU as a National Leader in Internet Safety

While a multitude of information from a host of sources exists on how to keep children safe on the Internet, there is not a unified effort to combine it all and get it to the right people. This is not a plan to teach college students about Internet safety. This is a proposal to begin much earlier, targeting middle-school aged children and their parents, many of whom have no idea of the dangers – and opportunities – that exist in cyberspace